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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN5
All Species:
25.45
Human Site:
T345
Identified Species:
50.91
UniProt:
O15484
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15484
NP_004046.2
640
73169
T345
I
K
C
R
V
I
N
T
S
H
L
S
I
H
K
Chimpanzee
Pan troglodytes
XP_001146965
641
74541
N345
N
V
C
R
N
V
N
N
P
I
F
G
R
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542293
640
73142
T345
I
K
C
R
L
I
N
T
S
Y
L
S
V
H
K
Cat
Felis silvestris
Mouse
Mus musculus
O08688
640
72936
T345
I
K
C
R
L
I
N
T
S
Y
L
S
I
H
K
Rat
Rattus norvegicus
Q8R4C0
640
73046
T345
I
K
C
R
L
I
N
T
S
Y
L
S
I
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518356
408
46381
S141
D
D
P
L
K
N
R
S
G
G
C
I
N
H
K
Chicken
Gallus gallus
Q92177
810
93542
D412
E
I
C
N
L
T
P
D
T
L
E
A
D
K
L
Frog
Xenopus laevis
NP_001080808
642
73235
T345
I
M
C
R
L
I
N
T
S
Y
L
S
I
Y
K
Zebra Danio
Brachydanio rerio
XP_001345114
642
73723
T345
I
L
C
R
L
I
N
T
S
Y
L
S
I
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q11002
828
93944
D389
E
I
C
N
L
S
P
D
S
L
T
E
D
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22036
648
73596
T355
S
L
C
Q
L
F
N
T
S
V
F
S
F
S
R
Sea Urchin
Strong. purpuratus
XP_792213
642
72430
K346
V
I
C
R
M
P
N
K
T
Y
L
S
L
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
N.A.
92
N.A.
92.1
90.6
N.A.
51.4
30.8
73.9
71.6
N.A.
30.7
N.A.
40.1
47.6
Protein Similarity:
100
65.5
N.A.
95.6
N.A.
96
94.8
N.A.
57.3
46.9
86.2
83.8
N.A.
45.2
N.A.
57.2
64.9
P-Site Identity:
100
20
N.A.
80
N.A.
86.6
86.6
N.A.
13.3
6.6
73.3
80
N.A.
13.3
N.A.
33.3
33.3
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
100
N.A.
20
26.6
93.3
93.3
N.A.
26.6
N.A.
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
92
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
9
0
0
0
0
0
17
0
0
0
0
17
0
0
% D
% Glu:
17
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
17
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
9
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
50
0
% H
% Ile:
50
25
0
0
0
50
0
0
0
9
0
9
42
0
0
% I
% Lys:
0
34
0
0
9
0
0
9
0
0
0
0
0
17
59
% K
% Leu:
0
17
0
9
67
0
0
0
0
17
59
0
9
0
9
% L
% Met:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
17
9
9
75
9
0
0
0
0
9
0
0
% N
% Pro:
0
0
9
0
0
9
17
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
17
9
% Q
% Arg:
0
0
0
67
0
0
9
0
0
0
0
0
9
0
17
% R
% Ser:
9
0
0
0
0
9
0
9
67
0
0
67
0
9
0
% S
% Thr:
0
0
0
0
0
9
0
59
17
0
9
0
0
0
0
% T
% Val:
9
9
0
0
9
9
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
50
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _